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Vitamin B3 as Inositol Hexanicotinate
  • No Flush Form
  • Promotes healthy cardiovascular support as well as blood flow andcell energy metabolism*
  • Vitamin B3 is a key nutrient involved in energy metabolism, formation of skin and digestive tissues*


Premier Niacin contains vitamin B3 as inositol hexanicotinate (IHN), a form of no-flush niacin. Vitamin B3 promotes healthy cardiovascular support and is a key component involved in many aspects of energy metabolism.

The coenzymes of vitamin B3 (NAD and NADP) assist in metabolic processes including the breakdown and utilization of fats, carbohydrates and protein. IHN also supports blood flow and healthy pancreas utilization.


Serving Size 1 Capsule
Servings Per Container 60

  • Niacin375 mg         
  • Inositol 91 mg (as Inositol Hexanicotinate)
Other Ingredients: Plant-Source Capsule (cellulose, water)

Recommended Usage:

Take 1 capsule, daily or as directed by your healthcare professional.



General Benefits of Niacin (Vitamin B3)

  1. Cholesterol Regulation: Niacin is well-known for its ability to manage blood lipid levels, and it can lower bad cholesterol (LDL) levels while increasing good cholesterol (HDL) levels.

  2. Cardiovascular Health: The lipid-modifying effects of niacin contribute to its ability to maintain heart health, and it may reduce the risk of cardiovascular diseases.

  3. Brain Function: Niacin plays a role in brain function and may help in preventing or managing cognitive decline and some psychiatric conditions.

  4. Skin Health: It may have a protective effect against sun damage and other forms of skin damage, potentially helping to prevent skin cancer.

  5. Digestion: It aids in the normal functioning of the digestive system and appetite regulation.

  6. Joint Mobility: It can improve joint mobility and may help in reducing inflammation and pain in the joints.

Inositol Hexanicotinate

  1. Flush-Free Niacin: One of the main reasons people choose inositol hexanicotinate is that it is often marketed as a "flush-free" niacin, meaning it doesn't cause the flushing (skin redness, warmth, and itching) commonly associated with niacin supplementation.

  2. Slow Release: The structure of inositol hexanicotinate allows for a slower release of niacin in the body compared to other forms, potentially leading to prolonged effects.

  3. Blood Flow: Some proponents suggest that it can support healthy blood flow, although the evidence for this claim is not robust.*

Anti-aging effects:

Vitamin B3, including its form as Inositol Hexanicotinate, has been studied for potential anti-aging properties, particularly concerning skin health and cellular aging. Here are some ways in which Vitamin B3 may possess anti-aging properties:

1. Skin Health:

  • Sun Protection and Repair: Niacinamide, a form of Vitamin B3, has been shown to protect skin cells from ultraviolet (UV) light, repair DNA damage, and reduce the incidence of nonmelanoma skin cancers in high-risk individuals.
  • Anti-Inflammatory Effects: Vitamin B3 has anti-inflammatory effects on the skin, which can be beneficial for inflammatory skin conditions and may reduce skin aging signs like redness and blotchiness.
  • Improves Skin Barrier Function: It can improve the skin barrier function, maintaining skin hydration, reducing transepidermal water loss, and potentially improving the appearance of aging skin.

2. Cellular Aging:

  • Sirtuin Activation: Some research indicates that niacin might activate sirtuins, a group of proteins that have been linked to longevity due to their role in regulating cellular health and metabolism.

3. Cognitive Protection:

  • Niacin has neuroprotective effects and has been associated with a decreased risk of neurodegenerative diseases, potentially contributing to the preservation of cognitive function with aging.

4. Metabolic Effects

  • Improved Metabolism: By being a component of coenzymes involved in cellular metabolism, niacin plays a role in maintaining healthy cellular function, which is crucial for combating aging.
  • Lipid Regulation: The lipid-regulating effects of niacin can also be considered as contributing to anti-aging, given the role of lipid metabolism in aging and age-related diseases.

5. Inositol Effects:

  • Inositol, a component of Inositol Hexanicotinate, is also essential for various cellular functions and may have additional anti-aging benefits, such as influencing insulin signaling and neurotransmitter modulation.
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