Description:

Activated methylcobalamin B12 for methylation, energy, and nervous system support*

Methylcobalamin 1000 mcg delivers 1,000 mcg of methylcobalamin—the bioactive coenzyme form of vitamin B12 practitioners choose for methylation, homocysteine balance, and neurological health.*

Methylcobalamin bypasses conversion steps required by cyanocobalamin, making it a staple in MTHFR-sensitive and repletion protocols.*

Product highlights

• 1,000 mcg methylcobalamin per capsule‡
• Activated coenzyme B12 form‡
• Supports methylation and nervous system function‡
• Hypoallergenic capsule‡

Who is this for

Methylcobalamin suits adults who need activated B12 repletion:*

• Documented low B12 under practitioner supervision.*
• Clients with MTHFR variants avoiding cyanocobalamin.*
• Vegetarians and older adults with reduced B12 absorption.*
• Protocols supporting homocysteine balance.*
• Sensitive patients requiring Pure Encapsulations purity.*

The Pure Encapsulations Difference

Pure Encapsulations formulates for sensitive patients: hypoallergenic ingredients, verifiable science, and manufacturing in NSF-GMP-registered facilities.

Coenzyme B12 in a hypoallergenic capsule without hidden allergens or artificial preservatives.

Ingredients & supplement facts

Net wt 60 capsules · 60 servings (1 capsule per serving)

Suggested use

• Take 1 capsule daily, with a meal, or as directed by your healthcare professional.
• Separate from high-dose folate formulas if your clinician is titrating B vitamins.
• Store in a cool, dry place with the lid tightly closed.
• If pregnant or lactating, consult your physician before use.

Science & Research

Methylcobalamin is a bioactive coenzyme form of vitamin B12 involved in methylation, red blood cell formation, and neurological function.

Frequently asked questions

How is this different from B-12 Folate?

B-12 Folate pairs B12 with Metafolin^® folate. Use this SKU when your clinician targets B12 alone.

Can I take this with my multivitamin?

Review total B12 from all sources to avoid excessive intake unless directed.

Can I combine this with other supplements?

Many practitioner protocols combine complementary formulas; review totals and interactions with your clinician.

Is this suitable for vegetarians?

Review the label for capsule or softgel materials; most Pure Encapsulations formulas use vegetarian capsules unless noted as softgels with gelatin.

How long does one bottle last?

One capsule daily equals a 60-day supply per 60-capsule bottle.