Description:

Activated B-complex with extra B5, B6, and B12 for energy metabolism*

B-Complex Plus combines the full spectrum of B vitamins with enhanced B5, B6, and B12—using activated folate as Metafolin^® L-5-MTHF and methylcobalamin for clients who need reliable methylation and energy support.*

B vitamins drive carbohydrate metabolism, neurotransmitter synthesis, and homocysteine balance. This practitioner-grade formula emphasizes bioactive forms in a hypoallergenic capsule suitable for daily use or targeted repletion.*

Product highlights

• Broad-spectrum B-complex with activated forms‡
• Extra B5, B6, and B12 for metabolic support‡
• Includes Metafolin^® L-5-MTHF and methylcobalamin‡
• Supports energy production and nervous system health‡

Who is this for

B-Complex Plus fits adults who want activated B vitamins without a multi-capsule regimen:*

• Clients supporting methylation pathways with methylfolate and methylcobalamin.*
• Individuals addressing fatigue, stress, or high metabolic demand under clinician care.*
• Vegetarians and older adults whose B12 or folate status needs attention.*
• Anyone separating B-vitamin support from a standalone multivitamin per practitioner plan.*
• Sensitive patients who require Pure Encapsulations quality and purity standards.*

The Pure Encapsulations Difference

Pure Encapsulations formulates for sensitive patients: hypoallergenic ingredients, verifiable science, and manufacturing in NSF-GMP-registered facilities.

Activated folate and B12 forms support methylation without hidden soy, gluten, or artificial preservatives.

Ingredients & supplement facts

Net wt 120 capsules · 120 servings (1 capsule per serving)

Full panel includes thiamin, riboflavin, niacin, B6, folate as Metafolin^®, B12 as methylcobalamin, biotin, pantothenic acid, and inositol. See the supplement facts image for complete quantitative values.

Suggested use

• Take 1 capsule daily, with a meal, or as directed by your healthcare professional.
• May be taken in the morning to support daytime energy metabolism.
• Review total B-vitamin intake if also using a multivitamin or methylation formula.
• Store sealed in a cool, dry place.
• If pregnant or lactating, consult your physician before use.

Science & Research

B vitamins function as coenzymes in energy metabolism, nervous system signaling, and homocysteine metabolism. Activated folate and methylcobalamin forms are often preferred when methylation support is a clinical goal.

Frequently asked questions

What is Metafolin^®?

Metafolin^® is a branded, bioactive form of folate (L-5-MTHF) that bypasses some conversion steps required by folic acid.

Can this replace my multivitamin?

B-Complex Plus is a targeted B formula, not a full multivitamin. Pair with other nutrients as your practitioner directs.

Will B vitamins keep me awake?

Some individuals prefer morning dosing. If sleep is affected, take earlier in the day or adjust with your clinician.

How long does one bottle last?

At one capsule daily, a 120-capsule bottle provides a four-month supply.

Is this suitable for vegetarians?

Capsules are vegetarian. Review the label with your practitioner if you follow a strict dietary protocol.